Job market candidates use Beamer. It definitely looks nice. Also, as part of the audience, I really like to know how many slides and concepts remain. If there is a lot left, I leave my slightly irrelevant questions for after the talk. That said, PowerPoint is so easy! Especially when going back and forth with coauthors making changes.
Solution: Jason Kirwin just blogged about a nice, easy way to convert PowerPoint slides to Beamer. Just click here.